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Doxycycline Hyclate

CAS number: 24390-14-5

Molecular formula: C22H24N2O8.HCl

molecular weight: 480.90

Chemical structure:

Producers shown on SFDA

(Record date:09/09/2021)

Producer

Documents

GMP Valid till(based on SFDA)

Kunshan HuaSu Biotechnology Co., Ltd. 

GMPValid till November 2022

Zhengzhou Fuyuan Animal Pharmaceutical Co., Ltd.

GMP
Valid till January 2026

Yangzhou LianBo Pharmaceutical Co., Ltd.

GMP
Valid till August 2025

Henan Houyi Pharmaceutical Co., Ltd.

GMP
Valid till June 2025

Hebei Jiupeng Pharmaceutical Co., Ltd. 

GMP
Valid till December 2023

Henan Province Aobang Biotechnology Co., Ltd.

GMP
Valid till August 2022

Jiaozuo Kaisen Pharmaceutical Co., Ltd.

GMP
Valid till September 2021

Producers shown on EP

(Quoted from EP website;record date:09/09/2021)

Substance
Certificate Holder
Certificate Number
Issue Date
Status
End date
Type
Doxycycline hyclate
Shanghai International Pharmaceutical Co., Ltd. CN 200 051 Shanghai
  R2-CEP 1992-018-Rev 00
19/02/2004
WITHDRAWN BY EDQM
22/10/2010
Chemistry
Doxycycline hyclate
KUNSHAN CHEMICAL AND PHARMACEUTICAL FACTORY CN 215 337 Kunshan City
  R0-CEP 2003-225-Rev 00
15/04/2005
WITHDRAWN BY EDQM
02/07/2008
Chemistry
Doxycycline hyclate
Ranbaxy Laboratories Limited IN 122 015 Gurgaon
  R1-CEP 1997-002-Rev 04
14/11/2014
WITHDRAWN BY HOLDER
24/03/2015
Chemistry
Doxycycline hyclate
Hebei Dongfeng Pharmaceutical Co., Ltd CN 057 150 Handan City
  R1-CEP 2004-163-Rev 00
01/06/2011
WITHDRAWN BY HOLDER
27/06/2016
Chemistry
Doxycycline hyclate
RAKS PHARMA PVT. LTD. IN 531 021 Visakhapatnam
  R0-CEP 2014-175-Rev 02
18/08/2020
VALID
/Chemistry
Doxycycline hyclate
Hovione PharmaScience Limited MO Taipa
  R1-CEP 1996-066-Rev 06
05/10/2020
VALID
/Chemistry
Doxycycline hyclate
KAIFENG PHARMACEUTICAL (GROUP) CO., LTD. CN 475 003 Kaifeng
  R1-CEP 2001-038-Rev 02
19/03/2015
VALID
/Chemistry
Doxycycline hyclate
YANGZHOU LIBERTY PHARMACEUTICAL CO., LTD. CN 225 127 Yangzhou
  R1-CEP 2000-165-Rev 06
26/04/2019
VALID
/Chemistry
Doxycycline hyclate
YANCHENG SUHAI PHARMACEUTICAL CO., LTD. CN 224 100 Dafeng District, Yancheng City
  R1-CEP 1999-100-Rev 04
25/06/2018
VALID
/Chemistry


Producer:Kunshan Chemical & Pharmaceutical Co., Ltd. was founded in 1981, specializing in the production of doxycycline series products for nearly 40 years. We are a new chemical production base integrating pharmaceutical R & D, production and export according to the requirements of modern pharmaceutical enterprises.

The product doxycycline monohydrate has passed the FDA certification, obtained the European COA certificate and the GMP certificate of the Ministry of agriculture of China.

Staff size:200-299 persons

Registered capital:RMB 6685.128439 million


Producer:Zhengzhou Fuyuan Animal Pharmaceutical Co., Ltd., established in 2002, is composed of three economic entities: Fuyuan animal protection, Fuyuan Chemical Industry and Fuyuan Technology. The company mainly produces and sells veterinary APIs and preparations. The company has passed GMP and FDA certification.

Staff size:50-99 persons

Registered capital:RMB 100 million


Producer:Yangzhou LianBo Pharmaceutical Co., Ltd. is a pharmaceutical manufacturer jointly established by Jiangsu Lianhuan Pharmaceutical Group Co., Ltd. (stock code 600513) and Hong Kong Bohua Group Co., Ltd. The company mainly produces synthetic pharmaceutical raw materials and pharmaceutical intermediates,the main products have passed the certification of FDA and many EU countries.

Staff size:700-799 persons

Registered capital:RMB 100 million


Producer:Henan Houyi Pharmaceutical Co., Ltd. is subordinate to Henan Houyi industrial group. The company covers an area of 800 mu, with a fermentation tonnage of 4000 tons and a synthesis capacity of 13800 tons. After completion, it will be a large production base of veterinary API in the Central Plains.

The company's main product production line has passed GMP acceptance, and the annual sales of sulfamethoxam and Cyclopropylamine are 500 tons and 1000 tons respectively; After tylosin and acetylisovaleryl tylosin are launched, the annual output can reach 500 tons and 200 tons.

Staff size:50-99 persons

Registered capital:RMB 128 million


Producer:Hebei Jiupeng Pharmaceutical Co., Ltd. is a medium-sized pharmaceutical and chemical enterprise. It was founded in 1987. The company covers an area of more than 200 mu. It has eight production workshops such as dehydrated oxytetracycline, doxycycline, chemical and power, and professional service units such as quality inspection center. All workshops have passed GMP certification, and the main products doxycycline hydrochloride and azithromycin API have been exported to more than 30 countries and regions in the world.
Staff size:100-199 persons

Registered capital:RMB 50 million


Producer:Henan Province Aobang Biotechnology Co., Ltd., established in 2003, has established a 18000 square meter GMP production base, with domestic first-class veterinary drug processing and testing equipment and Chinese and Western drug production lines. In addition to the re inspection of powder / powder / premix / non chlorine disinfectant (liquid), a new non sterile API workshop was built.

Staff size:About 50 persons
Registered capital:RMB 20 million


Producer:Jiaozuo Kaisen Pharmaceutical Co., Ltd. was founded in 2006, covering an area of more than 50000 square meters. It has newly built a powder injection production line, three water injection production lines, five solid production lines, two disinfectant production lines, doxycycline raw material production line and traditional Chinese medicine extraction production line. It will achieve an annual production capacity of 10 million bags of veterinary powder, 100 million pieces of water injection and powder injection, 500000 bottles of disinfectant and 450 tons of doxycycline API.

Staff size:/

Registered capital:RMB 15 million


For supply and market information, please feel free to contact Mr. Paul, paulzhang@yinuopharmchem.com, WhatsApp: +8618402846978